The 27-year-old Canadian fired a six-under 66 for the second day running to finish on 20-under 268 after a rollercoaster of a final round at TPC San Antonio.
J.T. Poston, Abraham Ancer, Brian Stuard and Jhonattan Vegas are the group at five under.
A group of six players, including headliners Jordan Spieth and Rickie Fowler, were left in second place after the overnight leader's hole-in-one.
Starting his round at the 10th, he was plodding along at even-par after seven holes, but birdied the next two with putts of five feet before slipping with a bogey at the first.
South Korea s Kim Si-woo fired a brilliant hole-in-one to surge into a four-shot lead at the Valero Texas Open in San Antonio on Friday. After a string of four pars, the former University of Texas star mixed in a pair of birdies against his lone bogey of the day.
Spieth finished second in the Texas Open in 2015.
Russian Federation opposes USA plan for more North Atlantic Treaty Organisation ships in Black Sea
Pence threatened that if Turkey completes the purchase, Turkey will risk expulsion from the joint F-35 program. The S-400, they say, is created to detect and shoot down stealth fighters like the F-35.
"I think if this were a 72-hole event, I have a chance to win based on the way I've played the last three days", Spieth said, according to the Associated Press.
"To birdie the last two holes is really big for me right now as I'm looking to gain confidence under pressure and kind of test some of the stuff I've been working on", Spieth said, according to USA Today. "Still didn't hit many fairways, but it felt better, if that makes sense".
If you want to watch a live stream of the TV broadcasts, the Golf Channel and NBC (available live in most markets) are two of 85-plus live-TV channels included in the main FuboTV bundle, which is largely tailored towards sports. "It doesn't seem as though we're going to get the normal south Texas conditions".
Jordan Spieth has not recorded a top ten on the PGA Tour since the Open Championship a year ago but this week, back on a golf course on which he finished runner-up the last time he played the event, he is within striking distance heading into the weekend.
NOTES: Defending champion Andrew Landry is in a tie for 51st at 1 under.
Rod Pampling and Aaron Baddeley made steady starts to finish one under but Curtis Luck (73), John Senden (74) and Cameron Davis (74) struggled at TPC San Antonio. "It was all of a 3-wood". Spieth, who has fallen to No. 32 in the world rankings, is one of 15 players in the field who also have a spot in next week's Masters.