Thomas Muller, Jerome Boateng and Mats Hummels were all informed Tuesday that they were no longer in Low's plans, part of an ongoing shake-up following Germany's woeful performance at last year's World Cup.
Boateng was one of the key figures in Germany's successful World Cup campaign in Brazil five years ago, starting the final at centre-back alongside Hummels.
Bayern slammed the "irritating and questionable" timing of Low's announcement that he will never pick Thomas Müller, Mats Hummels and Jerome Boateng again.
"We want to give the team a new look", Loew said.
Germany face Serbia in a friendly before taking on Netherlands in a Euro 2020 qualifying match later this month, and Low said 2019 would bring "a new start".
'2019 is a new beginning for the Germany national team, ' he said.
'I am convinced that this is the right step.
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"But it's mostly the character of the decision that I don't understand". "Mats, Jerome and I are still in a position to play football at the highest level".
"In my view, it wasn't necessary to close the door to the national team for three well-deserving players", said 50-year-old.
Loew's decision heralds the end of an impressive worldwide career for Mueller, who broke through as a raw 20-year-old at the 2010 World Cup and went on to score 38 goals in 100 appearances. I was totally dumbfounded by this decision out of the blue by the national coach.
"The young national players will have the space they need to fully develop, and now they have to take responsibility."
"It was important to me personally to explain to the players and managers of Bayern my thoughts and plans today", Low was quoted as saying to renowned Germany newspaper Bild.
Bayern added their "surprise" that the announcement took place on the same day Low made an unannounced visit to Bayern's training ground. I was always proud to wear the jersey, I've given everything, I want to thank you for your support, it was an incredible journey'.
'I am sad about this news because it has always been the greatest thing for me to represent my country.
"I was young myself and reliant on older players to make room for me". Of course, I would have wished for another farewell for us.