This is the second time that Whittaker was scheduled to defend the UFC middleweight title in Australia, only for injury to prevent such a thing from happening.
It is understood Whittaker started complaining to his coaching staff late on Saturday evening of pain in his abdomen. He will have surgery to resolve the issue immediately.
Extra weight was added to the Adesanya-Silva fight when UFC president Dana White announced on Friday that it would be for the No.1 middleweight contender spot.
The cancellation of the bout poses the question of whether or not Gastelum will get the first shot at Whittaker's belt when he returns from injury, with the victor of the fight between Adesanya and Silva guaranteed a title shot.
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Per Okamoto, the hernia was not related to Whittaker's weight cut.
Despite being elevated to the main event, Adesanya's bout will remain a three-round fight.
UFC legend Anderson Silva broke down in tears as he prepares to make his long-awaited return at UFC 234 in Australia. Now, Adesanya gets the biggest fight of his career thanks to a UFC card being suddenly Whittaker-less again.