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It's been reported that a small plane came apart in the air, dropping parts throughout a neighbourhood in southern California.

A man puts out fire on a piece of debris from a plane that crashed into a house in a residential neighborhood in Yorba Linda, California, US, February 3, 2019, in this still image from video obtained from social media.

Allen Kenitzer, a spokesman for the Federal Aviation Administration, said the aircraft went down under unknown circumstances.

Joshua Nelson said Sunday on Twitter.

The male pilot, who was the only person in the twin-engine plane, and four people in the Yorba Linda house that caught fire died Sunday, Orange County Sheriff's Lt. Cory Martino said at a news conference Sunday night. The home can be seen with scorch marks on its facade and broken windows, among other damage.

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According to the OCFA PIO on Twitter, at least two people are dead and two patients were transported to local hospitals.

Another tweeted: "Pretty sure we just saw a plane crash into a neighborhood". "I thought a bomb was dropped or something cuz I heard a plane engine moving in close and then my house shook on impact".

Two other people were injured in the incident.

Footage from the scene showed a blaze engulfing one of the houses in the suburban area with people shouting to keep away from the building.

A propeller and debris in the driveway of a home.